Article

Contribution of extracellular vesicles to human pulmonary arterial smooth muscle cell dysfunction in congenital heart disease-associated pulmonary arterial hypertension

2022-03-15

Abstract excerpt

<h4>Background: </h4> Pulmonary arterial hypertension (PAH) is a common complication of congenital heart disease (CHD). Extracellular vesicles (EVs) are small endosome- derived membrane microvesicles that play a prominent role in intercellular communication by carrying signaling molecules, such as proteins, mRNAs, and microRNAs. <h4>Methods:</h4> We obtained peripheral blood from irreversible CHD-PAH group and rev...

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Literature Corpus work: 3483cc69-bedc-592f-9d77-7377805eb06d
DOI: 10.21203/rs.3.rs-1425524/v1

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