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Article

Induction of pulmonary hypertensive changes by extracellular vesicles from monocrotaline-treated mice.

Cardiovascular research - 1 Dec 2013

Aliotta Jason M, Pereira Mandy, Amaral Ashley, Sorokina Arina, Igbinoba Zenas, Hasslinger Alexander, El-Bizri Rabih, Rounds Sharon I, Quesenberry Peter J, Klinger James R

Abstract excerpt

AIMS: Circulating endothelium-derived extracellular vesicles (EV) levels are altered in pulmonary arterial hypertension (PAH) but whether they are biomarkers of cellular injury or participants in disease pathogenesis is unknown. Previously, we found that lung-derived EVs (LEVs) induce bone marrow-derived progenitor cells to express lung-specific mRNA and protein. In this study, we sought to determine whether LEV...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23867631
DOI: 10.1093/cvr/cvt184
PMCID: PMC3826701

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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