Article

Unveiling the functional heterogeneity of endogenous tissue extracellular vesicles in skeletal muscle through multi-omics

2024-11-21

Abstract excerpt

Extracellular vesicles (EVs) have emerged as promising tools for the development of disease biomarkers and therapeutics because they can transfer various bioactive cargos between cells in vivo . A better understanding of the heterogeneous properties of EVs in vivo may provide insights into their biological roles and clinical translation potential. As a proof-of-concept, we report that different EV subpopulations...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 45dfbff8-01d8-5f4b-b9e2-943c3a088641
DOI: 10.1101/2024.11.20.624461

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Unveiling the functional heterogeneity of endogenous tissue extracellular vesicles in skeletal muscle through multi-omicsDOI 10.1101/2024.11.20.624461Read

Biogenesis and function of extracellular vesicles in pathophysiological processes of skeletal muscle atrophySemantic proximity Read

Molecular and Epigenetic Basis of Extracellular Vesicles Cell Repair Phenotypes in Targeted Organ-specific Regeneration.Semantic proximity Read

Extracellular Vesicles: How Drug and Pathology Interfere With Their Biogenesis and FunctionSemantic proximity Read

Influences of age, race, and sex on extracellular vesicle characteristicsSemantic proximity Read

Small extracellular vesicles from mesenchymal stromal cells: the next therapeutic paradigm for musculoskeletal disordersSemantic proximity Read

Experimental and Biological Insights from Proteomic Analyses of Extracellular Vesicle Cargos in Normalcy and DiseaseSemantic proximity Read

Small Extracellular Vesicles by Nucleus Pulposus Cells Maintain Niche and Cell Homeostasis via Receptor Shuffling and Metabolic Enzyme SupplementsSemantic proximity Read

Microvesicles as promising biological tools for diagnosis and therapySemantic proximity Read

Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of CardiologySemantic proximity Read

RNA Cargo Profiling of Muscle Extracellular Vesicles Reveals Candidate Biomarkers of Disease Activity and Muscle Degeneration in FSHDSemantic proximity Read

A Panorama of Extracellular Vesicle Applications: From Biomarker Detection to Therapeutics.Semantic proximity Read

Extracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditionsSemantic proximity Read