Article
Associations between genetically predicted concentrations of plasma proteins and the risk of prostate cancer.
BMC cancer - 27 Jul 2024
Sun Wenguo, Li Haoming, Shi Wenjie, Lv Quanlong, Zhang Weili
Abstract excerpt
BACKGROUND: Prostate cancer (PCa) is a leading cause of cancer-related death in men. Understanding the proteomic landscape associated with PCa risk can provide insights into its molecular mechanisms and pave the way for potential therapeutic interventions. METHODS: A proteome-wide Mendelian randomization (MR) analysis was employed to determine associations between genetically predicted protein concentrations in...
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