Article

Ultrasensitive Detection of Chromosomal Instability in Ascites as a Novel Diagnostic for Peritoneal Carcinomatosis

2026-02-16

Abstract excerpt

<title>Abstract</title> <p>Background Diagnosing peritoneal carcinomatosis (PC) remains challenging. This study aims to evaluate the value of ascites chromosomal instability (CIN) analysis in the diagnosis of PC. Methods We performed low-coverage whole-genome sequencing on 50 human ascites samples. CIN was profiled using ultrasensitive chromosomal aneuploidy detection (UCAD), and its diagnostic performance was...

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Literature Corpus work: 344928f7-b4c3-5f12-b0db-ee69b447d0ad
DOI: 10.21203/rs.3.rs-8280082/v1

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