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Article

Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamics

1 Jan 2022

Abstract excerpt

Epithelial ovarian cancer remains the lethal gynecological malignancy in women. The representative histotype is high-grade serous carcinoma (HGSC), and most patients with HGSC present at advanced stages with peritoneal dissemination. Since the peritoneal dissemination is the most important factor for poor prognosis of the patients, complete exploration for its molecular mechanisms is mandatory. In this narrative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36032027
DOI: 10.3802/jgo.2022.33.e83

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