Article

Resident cardiac macrophages are not required for normal atrioventricular node conduction

2026-02-12

Abstract excerpt

<h4>SUMMARY</h4> Resident cardiac macrophages are understood to facilitate atrioventricular (AV) node conduction because they purportedly couple to AV node myocytes via connexin43 (Cx43) containing gap junctions. We tested this mechanism using biophysical modelling, high-resolution imaging of mouse and human AV conduction tissue, and pharmacological macrophage depletion. In silico , coupling macrophage membrane...

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Literature Corpus work: 3425893c-6965-59eb-975b-2994fda03ee4
DOI: 10.64898/2026.02.11.704506

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