Article

Endurance exercise remodels pulmonary vein sleeve myocytes and promotes a proarrhythmic atrial substrate

2025-02-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Atrial fibrillation (AF) susceptibility is heightened in endurance athletes but the underlying mechanisms are incompletely understood. Because pulmonary vein (PV) myocyte triggers are critical determinants of AF, we investigated PV electrophysiological remodelling in animal models of the athlete’s heart. <h4>METHODS</h4> The following experiments were performed in canines a...

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Literature Corpus work: 722682ba-7528-5180-ae08-5d859b70e31b
DOI: 10.1101/2025.02.12.638004

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