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Article

Epicardial fat drives macrophage response in atrial cardiomyopathy

2025-05-22

Abstract excerpt

<title>Abstract</title> <p>Inflammation is associated with atrial fibrillation (AF), but its precise impact on the long-term progression of AF substrate, also called atrial cardiomyopathy (ACM), remains debated. Here, using spatial gene expression analysis, macrophage subpopulations mainly confined to the epicardial fat depots were identified in human atria. In a mouse model of obesity and ACM, macrophage recruit...

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Literature Corpus work
40a95fb6-40c2-5e5a-aa7e-4e6b1354e047
DOI
10.21203/rs.3.rs-6455438/v1
Open publication

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Epicardial fat drives macrophage response in atrial cardiomyopathyDOI 10.21203/rs.3.rs-6455438/v1
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