Article

Distinct Genomic Features Between Osteosarcomas Firstly Metastasing to Bone and to Lung

2022-02-15

Abstract excerpt

<h4>Background: </h4> Osteosarcoma (OS) initially metastasing to bone only shows distinct biological features compared to osteosarcoma that firstly metastasizes to the lung, which suggests us underlying different genomic pathogenetic mechanism. However related-study is lacking. <h4>Methods: </h4>: We analyzed whole-exome sequencing (WES) data for 38 metastatic OS patients with different relapse patterns. Multiplex...

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Literature Corpus work: 341d89ef-0906-531d-b648-244fd12a9c54
DOI: 10.21203/rs.3.rs-1354631/v1

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