Article

CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes

2022-07-10

Abstract excerpt

Myelin is required for rapid nerve signaling and is emerging as a key driver of CNS plasticity and disease. How myelin is built and remodeled remains a fundamental question of neurobiology. Central to myelination is the ability of oligodendrocytes to add vast amounts of new cell membrane, expanding their surface areas by many thousand-fold. However, how oligodendrocytes add new membrane to build or remodel myelin...

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Literature Corpus work: 3419245a-b155-5e36-a049-f31d625f0cdc
DOI: 10.1101/2022.07.08.498895

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