Article
Prediction of antigen-responding VHH antibodies by tracking evolution of antibody along time course of immunization
2021-07-01
Abstract excerpt
Antibody maturation is the central function of the adaptive immune response. This process is driven by the repetitive selection of mutations that increase the affinity toward antigens. We hypothesized that precise observation of this process by high-throughput sequencing along time course of immunization will enable us to predict the antibodies reacting to the immunized antigen without any additional in vitro scr...
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Identifiers and source
- Literature Corpus work
- 3411d348-b88b-52c6-8351-33621a144e7a
- DOI
- 10.1101/2021.06.29.449501