Article

IL-6 stimulates a concentration-dependent increase in MCP-1 in immortalised human brain endothelial cells

2016-05-11

Abstract excerpt

Systemic inflammation is associated with neurodegeneration, with elevated interleukin-6 (IL-6) in particular being correlated with an increased risk of dementia. The brain endothelial cells of the blood brain barrier (BBB) serve as the interface between the systemic circulation and the brain microenvironment and are therefore likely to be a key player in the development of neuropathology associated with systemic i...

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Literature Corpus work: 336b58cb-28d6-5e78-a4c5-5d0092fdf3a3
DOI: 10.12688/f1000research.8153.2

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