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Article

Interleukin-6 stimulates circulating blood-derived endothelial progenitor cell angiogenesis in vitro.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Jan 2008

Fan Yongfeng, Ye Jianqin, Shen Fanxia, Zhu Yiqian, Yeghiazarians Yerem, Zhu Wei, Chen Yongmei, Lawton Michael T, Young William L, Yang Guo-Yuan

Abstract excerpt

Circulating blood endothelial progenitor cells (EPCs) contribute to postnatal vasculogenesis, providing a novel therapeutic target for vascular diseases. However, the molecular mechanism of EPC-induced vasculogenesis is unknown. Interleukin-6 plays multiple functions in angiogenesis and vascular remodeling. Our previous study demonstrated that the polymorphism (174G>C) in IL-6 gene promoter was associated with...

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Share to Cerebrovascular Disorders
Share to Cytokine Receptor gp130

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MAP Kinase Signaling System

Share to Mitogen-Activated Protein Kinase 1

Share to Mitogen-Activated Protein Kinase 3

Share to Neovascularization, Physiologic

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Identifiers

PMID: 17519976
DOI: 10.1038/sj.jcbfm.9600509
PMCID: PMC2581498

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STAT3

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