Article

miRNA-486-5p Promotes COPD Progression by Targeting HAT1 to Regulate the TLR4-Triggered Inflammatory Response of Alveolar Macrophages

2020-09-03

Abstract excerpt

<h4>Background: </h4> The aim of this study is to investigate the key regulatory miRNA-486-5p and underlying molecular mechanisms in chronic obstructive pulmonary disease (COPD) progression. <h4>Methods: </h4>: Aberrant miRNA expression in smokers compared to non-smokers and COPD compared to normal was analyzed using microarray datasets and reverse-transcriptase quantitative polymerase chain reaction (qPCR). ELISA...

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Literature Corpus work: 32ef0582-7e73-5ddf-823e-d89fa022333c
DOI: 10.21203/rs.3.rs-64780/v1

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