Epigenetic mechanisms in COPD: implications for pathogenesis and drug discovery

Abstract excerpt

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death worldwide. The growing burden of COPD is due to continuous tobacco use, which is the most important risk factor of the disease, indoor fumes, occupational exposures and also aging of the world's population. Epigenetic mechanisms significantly contribute to COPD pathophysiology. AREAS COVERED: This review focuses on...

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