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COVID-19 risk variant associations with chromatin remodelling, DNA maintenance and surfactant genes are infection dependent in the lung

2023-05-05

Abstract excerpt

During viral infection the structure of host chromatin is modified. It is generally assumed that these chromatin modifications will affect variant-gene mapping, and therefore gene expression. What is not clear is how limitations imposed by host germline risk affect the expression changes that occur with infection induced chromatin remodelling. Critically, this lack of information extends to how germline variants a...

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Identifiers and source

Literature Corpus work
32c7884d-6562-561b-9359-de385415e1b4
DOI
10.1101/2023.05.03.23289478
Open publication

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COVID-19 risk variant associations with chromatin remodelling, DNA maintenance and surfactant genes are infection dependent in the lungDOI 10.1101/2023.05.03.23289478
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