Article

Lung expression of genes encoding SARS-CoV-2 cell entry molecules and antiviral restriction factors: interindividual differences are associated with age and germline variants

2020-06-24

Abstract excerpt

Germline variants in genes involved in SARS-CoV-2 cell entry (i.e. ACE2 and TMPRSS2 ) may influence the susceptibility to infection, as may polymorphisms in genes involved in the innate host response to viruses (e.g. APOBEC3 family). We searched for polymorphisms acting, in lung tissue, as expression quantitative trait loci (eQTLs) for 15 candidate COVID-19 susceptibility genes, selected for their roles in virus...

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Literature Corpus work: 7bfa7bde-4370-55c8-930d-ad6f6fc41302
DOI: 10.1101/2020.06.24.168534

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