Article

ProtSyntax: a protein large language model for decoding post-translational modification syntax and function

2026-07-21

Abstract excerpt

Post-translational modifications (PTMs) expand protein function by encoding context-dependent regulatory states, and their dysregulation contributes to cancer, neurodegeneration and metabolic disease. However, existing methods treat PTMs as independent residue labels, limiting their ability to distinguish contextually permissible sites, model crosstalk and infer functional consequences. Here we introduce ProtSynta...

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Identifiers and source

Literature Corpus work: e63fe32d-b555-5884-84fb-a6c126f8c452
DOI: 10.64898/2026.07.18.739331

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