Article

Longitudinal increase in sleep problems is related to amyloid deposition in cortical regions with high <i>HOMER1</i> gene expression

2018-05-31

Abstract excerpt

Older adults who report more sleep problems tend to have elevated levels of the Alzheimer’s disease (AD) biomarker β-amyloid (Aβ), but the mechanisms responsible for this relationship are largely unknown. Molecular markers of sleep problems are now emerging from rodent research, yielding opportunities to generate hypotheses about the causes of the sleep-Aβ relationship. A major molecular marker of sleep deprivatio...

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Literature Corpus work: 32b39410-39f3-5c35-bc37-b017290a76d6
DOI: 10.1101/335612

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