Article

An ancient transcription factor functions as the master regulator of primary cilia formation

2025-11-29

Abstract excerpt

How ancient transcription factors are repurposed during evolution to drive the functional diversification of conserved organelles remains a fundamental question in biology. Although highly conserved in basic morphology, eukaryotic cilia vary extensively in their sizes and functions. Previously, we showed that an evolutionarily ancient transcription factor, X chromosome–associated protein 5 (Xap5), controls motile...

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Literature Corpus work: 329745df-dec4-504f-adf8-a40c81c92a1c
DOI: 10.1101/2025.11.28.691250

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