Article
Senescent cell clearance ameliorates temporal lobe epilepsy and associated spatial memory deficits in mice
2024-07-31
Abstract excerpt
Current therapies for the epilepsies only treat the symptoms, but do not prevent epileptogenesis (the process in which epilepsy develops). Many cellular responses during epileptogenesis are also common hallmarks of cellular senescence , which halts proliferation of damaged cells. Clearing senescent cells (SCs) restores function in several age-associated and neurodegenerative disease models. It is unknown whether...
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Identifiers and source
- Literature Corpus work
- 328fbf78-e62b-5eb6-af27-cf4736529577
- DOI
- 10.1101/2024.07.30.605784