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Article

AMD-associated genes encoding stress-activated MAPK pathway constituents are identified by interval-based enrichment analysis.

PloS one - 1 Jan 2013

SanGiovanni John Paul, Lee Phil H

Abstract excerpt

PURPOSE: To determine whether common DNA sequence variants within groups of genes encoding elements of stress-activated mitogen-activated protein kinase (MAPK) signaling pathways are, in aggregate, associated with advanced AMD (AAMD). METHODS: We used meta-regression and exact testing methods to identify AAMD-associated SNPs in 1177 people with AAMD and 1024 AMD-free elderly peers from 3 large-scale genotyping...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23940728
DOI: 10.1371/journal.pone.0071239
PMCID: PMC3734129

Genes

TGFB2
TGFBR2

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