Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potential mechanisms of epigenetic regulation in diabetic retinopathy from the perspectives of multi-omics

14 May 2025

Abstract excerpt

PURPOSE: Diabetic retinopathy (DR) is a significant complication of diabetes, with complex pathogenesis involving epigenetic modifications. This study aimed to explore the epigenetic regulatory mechanisms contributing to DR. METHODS: DR-related data, including DNA methylation, mRNA, and miRNA expression datasets, were obtained from the Gene Expression Omnibus database. Differential gene expression analysis was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to Retinal Diseases and Treatments
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40369608
DOI: 10.1186/s13098-025-01723-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potential mechanisms of epigenetic regulation in diabetic retinopathy from the perspectives of multi-omicsPMID 40369608Read ↗

DNA methylation in diabetic retinopathy: pathogenetic role and potential therapeutic targetsSemantic proximity Read ↗

Role of histone modification and DNA methylation in signaling pathways involved in diabetic retinopathySemantic proximity Read ↗

Identification and Validation of Genes Related to RNA Methylation Modification in Diabetic RetinopathySemantic proximity Read ↗

Identification of Key ncRNAs and ceRNA Network in DR via Bioinformation AnalysisSemantic proximity Read ↗

Epigenetic Mechanisms in the Pathogenesis of Diabetic RetinopathySemantic proximity Read ↗

Dissecting the Pathogenesis of Diabetic Retinopathy Based on the Biological ceRNA Network and Genome Variation Disturbance.Semantic proximity Read ↗

Identification of NLRP3 Inflammation-Related Gene Promoter Hypomethylation in Diabetic RetinopathySemantic proximity Read ↗

Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy.Semantic proximity Read ↗

Bioinformatics analysis of immune infiltration in human diabetic retinopathy and identification of immune-related hub genes and their ceRNA networksSemantic proximity Read ↗

Susceptibility and protective genes in diabetic retinopathy: A comprehensive single-cell RNA sequencing analysis.Semantic proximity Read ↗

Transcriptome analysis combined with Mendelian randomization screening for biomarkers causally associated with diabetic retinopathySemantic proximity Read ↗

Diabetic retinopathy: reversibility of epigenetic modifications and new therapeutic targetsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.