Article

Genomic and epigenomic re-categorization of congenital glioblastoma and desmoplastic infantile ganglioglioma

2022-07-26

Abstract excerpt

The recently updated World Health Organization classification of Central Nervous System (CNS) tumors, 5 th edition, (CNS5) reclassifies pediatric tumors according to their distinct molecular drivers, recognizing a new entity - infant-type hemispheric glioma (IHG). Defined by its unique epigenetic signature, and/or genomic fusions in ALK, ROS1, NTRK or MET gene, IHG subsumes many cases previously classified as cong...

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Literature Corpus work: 3231719d-50c1-5306-881c-ef8bd594b953
DOI: 10.21203/rs.3.rs-1832265/v1

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