Article
Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) Are Distinct Entities with Frequent BRAFV600 Mutations.
Molecular cancer research : MCR - 1 Oct 2018
Wang Anthony C, Jones David T W, Abecassis Isaac Joshua, Cole Bonnie L, Leary Sarah E S, Lockwood Christina M, Chavez Lukas, Capper David, Korshunov Andrey, Fallah Aria, Wang Shelly, Ene Chibawanye, Olson James M, Geyer J Russell, Holland Eric C, Lee Amy, Ellenbogen Richard G, Ojemann Jeffrey G
Abstract excerpt
Desmoplastic infantile ganglioglioma (DIG) and desmoplastic infantile astrocytoma (DIA) are extremely rare tumors that typically arise in infancy; however, these entities have not been well characterized in terms of genetic alterations or clinical outcomes. Here, through a multi-institutional collaboration, the largest cohort of DIG/DIA to date is examined using advanced laboratory and data processing techniques....
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