Mechanism of NLRP3 inflammasome activation

Abstract excerpt

Inflammasomes continue to generate interest in an increasing number of disciplines owing to their unique ability to integrate a myriad of signals from pathogen- and damage-associated molecular patterns into a proinflammatory response. This potent caspase-1-dependent process is capable of activating the innate immune system, initiating pyroptosis (an inflammatory form of programmed cell death), and shaping...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Heme Oxygenase-1 and Carbon Monoxide
• Share to Inflammasome and immune disorders
• Share to Kawasaki Disease and Coronary Complications