Article

Deficiency of acetyltransferase nat10 in zebrafish causes developmental defects in the visual function and behavior

2023-05-26

Abstract excerpt

N4-acetylcytidine (ac4C) is an epitranscriptomic modification of mRNA that is catalyzed by N-acetyltransferase 10 (NAT10), a critical factor known to influence mRNA stability. However, its role in development has not been investigated. In this study, we used CRISPR/Cas9 and RNAi technology to knock out and knock down nat10 , the zebrafish ortholog of human NAT10, and evaluated their effects on development, behavio...

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Literature Corpus work: 315ad2d5-8d65-5c3c-a62b-618d32b9e31f
DOI: 10.21203/rs.3.rs-2970743/v1

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