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Non-coding RNAs and chromatin: key epigenetic factors from spermatogenesis to transgenerational inheritance

20 Dec 2021

Abstract excerpt

Cellular fate and gene expression patterns are modulated by different epigenetic factors including non-coding RNAs (ncRNAs) and chromatin organization. Both factors are dynamic throughout male germ cell differentiation on the seminiferous tubule, despite the transcriptional inactivation in the last stages of spermatogenesis. Sperm maturation during the caput-to-cauda transit on the epididymis involves changes in...

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PMID: 34930477
DOI: 10.1186/s40659-021-00364-0

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