Applying a genetic risk score model to enhance prediction of future Multiple Sclerosis diagnosis at first presentation with optic neuritis: a cohort study in the UK Biobank

Abstract excerpt

<title>Abstract</title> <p>Optic neuritis (ON) is associated with numerous immune-mediated inflammatory diseases. After presenting for the first time with undifferentiated ON, up to 50% per cent of patients are subsequently diagnosed with multiple sclerosis (MS), sometimes many years later. Differentiating MS-ON from non-MS-ON in the acute setting is challenging but important. Initial treatment of MS-ON and non-M...

Topics

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• Algorithms
• Cohort Studies
• Environment
• Multiple Sclerosis
• Odds Ratio
• Predictive Value of Tests
• Quantitative Trait Loci
• Risk Assessment

Identifiers and source

Literature Corpus work

31110931-fefe-5550-8b91-d4445caa7cd9

DOI

10.21203/rs.3.rs-2383733/v1