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Article

IFI30 remoulds immune microenvironment and macrophage function to promote colorectal cancer and atherosclerosis

2025-12-19

Abstract excerpt

<title>Abstract</title> <p> Background Colorectal cancer (CRC) and atherosclerosis (AS) are both chronic inflammatory diseases that may share immune-related genes (IRGs) and regulatory mechanisms. This study aimed to identify commonly dysregulated IRGs in CRC and AS, and to investigate their clinical significance and molecular functions. Methods Transcriptomic, single-cell RNA sequencing (scRNA-seq), and somat...

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Literature Corpus work
30de179a-e4cf-5808-b64c-7ae4e3129e1e
DOI
10.21203/rs.3.rs-7551279/v1
Open publication

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IFI30 remoulds immune microenvironment and macrophage function to promote colorectal cancer and atherosclerosisDOI 10.21203/rs.3.rs-7551279/v1
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