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Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer’s disease and aging

2022-09-10

Abstract excerpt

Alzheimer’s disease (AD) is characterized by progressive neurodegeneration, but the specific events that cause cell death remain poorly understood. Death Induced by Survival gene Elimination (DISE) is a cell death mechanism mediated by short (s) RNAs acting through the RNA induced silencing complex (RISC). DISE is thus a form of RNA interference, in which G-rich 6mer seed sequences in the sRNAs (position 2-7) targ...

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Literature Corpus work
30d94bb3-24cd-516f-b204-37e7bb0e34c6
DOI
10.1101/2022.09.08.507157
Open publication

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Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer’s disease and agingDOI 10.1101/2022.09.08.507157
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