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Article

Socio-demographic and genetic risk factors for drug adherence and persistence across 5 common medication classes.

Nature communications - 23 Oct 2024

Cordioli Mattia, Corbetta Andrea, Kariis Hanna Maria, Jukarainen Sakari, Vartiainen Pekka, Kiiskinen Tuomo, Ferro Matteo, Perola Markus, Niemi Mikko, Ripatti Samuli, Lehto Kelli, Milani Lili, Ganna Andrea

Abstract excerpt

Low drug adherence is a major obstacle to the benefits of pharmacotherapies and it is therefore important to identify factors associated with discontinuing or being poorly adherent to a prescribed treatment regimen. Using high-quality nationwide health registry data and genome-wide genotyping, we evaluate the impact of socio-demographic and genetic risk factors on adherence and persistence for 5 common medication...

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PMID: 39443518
DOI: 10.1038/s41467-024-53556-z
PMCID: PMC11500092

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