Article

All-optical electrophysiology reveals behavior-dependent dynamics of excitation and inhibition in the hippocampus

2025-03-20

Abstract excerpt

<h4>Summary</h4> Understanding how neuronal integration is modulated by behavior is a fundamental goal in neuroscience. We combined voltage imaging with optogenetic depolarization to reveal how changes in excitatory (E) and inhibitory (I) inputs, modulate the spiking output, subthreshold dynamics, and gain of key genetically defined cell types in the CA1 region of the hippocampus. We imaged pyramidal cells (PCs),...

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Literature Corpus work: a658535a-aab2-5c06-9b11-3c388dd06979
DOI: 10.1101/2025.03.20.644347

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