Article

Immunoglobulin heavy constant gamma gene evolution is modulated by both the divergent and birth-and-death evolutionary models

2021-08-13

Abstract excerpt

Immunoglobulin G (IgG) is one of the five antibody classes produced in mammals as part of the humoral responses. This high-affinity antibody produced late in a primary immune response is responsible for protecting the organisms from infection. This protein’s heavy chain constant region is encoded by the Ig gamma gene ( Igγ ). In Humans, IgG has evolved into four subclasses with specialized effector functions. How...

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Literature Corpus work: 308e47a4-c1f0-50c5-a5d2-90415904f753
DOI: 10.1101/2021.08.12.456010

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