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NLRP3 in tumor-associated macrophages predicts a poor prognosis and promotes tumor growth in head and neck squamous cell carcinoma

2022-08-01

Abstract excerpt

The NLRP3 inflammasome plays cell- and tissue-specific roles in cancer, meaning that its activation in different tumors or cells may play different roles in tumor progression. We have previously described the tumor-promoting function of tumor-intrinsic NLRP3/IL-1β signaling in head and neck squamous cell carcinoma (HNSCC), but its role in immune cells remains unclear. In this study, we found that NLRP3 was highly...

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Identifiers and source

Literature Corpus work
3084990b-fc40-5842-8ef1-d6bc75cf0c16
DOI
10.21203/rs.3.rs-1907769/v1
Open publication

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NLRP3 in tumor-associated macrophages predicts a poor prognosis and promotes tumor growth in head and neck squamous cell carcinomaDOI 10.21203/rs.3.rs-1907769/v1
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