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NLRP3 Promotes Immune Escape by Regulating Immune Checkpoints: A Pan-cancer Analysis

2021-08-02

Abstract excerpt

<title>Abstract</title> <p>NLRP3 plays a pathogenic role in tumorigenesis by regulating innate and acquired immunity, apoptosis, differentiation, and intestinal microbes in tumors. In different tumors, NLRP3 plays different roles, and its mechanism is complex. Our research aimed to comprehensively investigated the role of NLRP3 in pan-cancers based on multi-omics data in the TCGA database. We found the expression...

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Literature Corpus work
fa7902fc-942a-598c-a09e-12f594ca001c
DOI
10.21203/rs.3.rs-626162/v1
Open publication

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NLRP3 Promotes Immune Escape by Regulating Immune Checkpoints: A Pan-cancer AnalysisDOI 10.21203/rs.3.rs-626162/v1
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