Article

Beneficial bacteria activate type-I interferon production via the cytosolic sensors STING and MAVS

2019-10-04

Abstract excerpt

Type-I interferon (IFN-I) cytokines are produced by innate immune cells in response to microbial infections, cancer and autoimmune diseases. These cytokines trigger protective responses in neighbouring cells through the activation of IFN-I stimulated genes. One of the most predominant pathways associated with IFN-I production is mediated by the cytosolic sensors STING and MAVS, intracellular adaptors that become a...

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Literature Corpus work: 197a7e2e-8392-5970-b523-5df3b5f20f08
DOI: 10.1101/792523

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