Article

Divergence of TORC1-mediated Stress Response Leads to Novel Acquired Stress Resistance in a Pathogenic Yeast

2023-06-20

Abstract excerpt

Acquired stress resistance (ASR) enables organisms to prepare for environmental changes that occur after an initial stressor. However, the genetic basis for ASR and how the underlying network evolved remain poorly understood. In this study, we discovered that a short phosphate starvation induces oxidative stress response (OSR) genes in the pathogenic yeast C. glabrata and protects it against a severe H 2 O 2 st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3068ca67-56b5-5e3c-9657-43763eeffc6e
DOI: 10.1101/2023.06.20.545716

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Divergence of TORC1-mediated Stress Response Leads to Novel Acquired Stress Resistance in a Pathogenic YeastDOI 10.1101/2023.06.20.545716Read

Genome-wide analysis of yeast stress survival and tolerance acquisition to analyze the central trade-off between growth rate and cellular robustness.Semantic proximity Read

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response PathwaySemantic proximity Read

Stress adaptation in a pathogenic fungusSemantic proximity Read

Structure-based engineering of Tor complexes uncovers different roles of two types of yeast TORC1sSemantic proximity Read

Stress signalling to fungal stress-activated protein kinase pathwaysSemantic proximity Read

Target of Rapamycin (TOR) Regulates Growth in Response to Nutritional SignalsSemantic proximity Read

Response of fission yeast to toxic cations involves cooperative action of the stress-activated protein kinase Spc1/Sty1 and the Hal4 protein kinase.Semantic proximity Read

Yippee-like protein Moh1 links gene expression to metabolism and selective stress resistance in <i>Saccharomyces cerevisiae</i>Semantic proximity Read

Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity.Semantic proximity Read

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulenceSemantic proximity Read

<i>Candida albicans’</i> inorganic phosphate transport and evolutionary adaptation to phosphate scarcitySemantic proximity Read

Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.Semantic proximity Read