Article

Arabidopsis 3β-Hydroxysteroid Dehydrogenases/C4-Decarboxylases are Essential for the Pollen and Embryonic Development

2023-10-03

Abstract excerpt

The biosynthesis of C27-29 sterols from their C30 precursor squalene involves C24-alkylation and removal of three methyl groups, including two at the C4 position. The two C4 demethylation reactions require a bifunctional enzyme known as 3β-hydroxysteroid dehydrogenase/C4-decarboxylase (3βHSD/D) that removes an oxidized methyl (carboxylic) group at C4 while simultaneously catalyzing the 3β-hydroxyl3-keto oxidation....

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Literature Corpus work: 3006ecf2-a6ad-5243-b57a-9ece404b43a2
DOI: 10.20944/preprints202310.0136.v1

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