Article
The SUD1 gene encodes a putative E3 ubiquitin ligase and is a positive regulator of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in Arabidopsis.
The Plant cell - 1 Feb 2013
Doblas Verónica G, Amorim-Silva Vítor, Posé David, Rosado Abel, Esteban Alicia, Arró Montserrat, Azevedo Herlander, Bombarely Aureliano, Borsani Omar, Valpuesta Victoriano, Ferrer Albert, Tavares Rui M, Botella Miguel A
Abstract excerpt
The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) enzyme catalyzes the major rate-limiting step of the mevalonic acid (MVA) pathway from which sterols and other isoprenoids are synthesized. In contrast with our extensive knowledge of the regulation of HMGR in yeast and animals, little is known about this process in plants. To identify regulatory components of the MVA pathway in plants, we performed a genetic...
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