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Article

Allelic mutant series reveal distinct functions for Arabidopsis cycloartenol synthase 1 in cell viability and plastid biogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 26 Feb 2008

Babiychuk Elena, Bouvier-Navé Pierrette, Compagnon Vincent, Suzuki Masashi, Muranaka Toshiya, Van Montagu Marc, Kushnir Sergei, Schaller Hubert

Abstract excerpt

Sterols have multiple functions in all eukaryotes. In plants, sterol biosynthesis is initiated by the enzymatic conversion of 2,3-oxidosqualene to cycloartenol. This reaction is catalyzed by cycloartenol synthase 1 (CAS1), which belongs to a family of 13 2,3-oxidosqualene cyclases in Arabidopsis thaliana. To understand the full scope of sterol biological functions in plants, we characterized allelic series of...

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Identifiers

PMID: 18287026
DOI: 10.1073/pnas.0712190105
PMCID: PMC2268602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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