Article
Arabidopsis cyp51 mutant shows postembryonic seedling lethality associated with lack of membrane integrity.
Plant physiology - 1 Aug 2005
Kim Ho Bang, Schaller Hubert, Goh Chang-Hyo, Kwon Mi, Choe Sunghwa, An Chung Sun, Durst Francis, Feldmann Kenneth A, Feyereisen René
Abstract excerpt
CYP51 exists in all organisms that synthesize sterols de novo. Plant CYP51 encodes an obtusifoliol 14alpha-demethylase involved in the postsqualene sterol biosynthetic pathway. According to the current gene annotation, the Arabidopsis (Arabidopsis thaliana) genome contains two putative CYP51 genes, CYP51A1 and CYP51A2. Our studies revealed that CYP51A1 should be considered an expressed pseudogene. To study the...
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