Article

Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia

2023-01-24

Abstract excerpt

<h4>Background</h4> In patients with diabetic microvascular complications, decreased perfusion or vascular occlusion, caused by reduced vascular diameter, is a common characteristic that will lead to insufficient blood supply. However, the regulatory mechanism remains undetermined and the treatment approach is lacking. <h4>Methods</h4> Gene expression of Aquaporin 1 ( AQP1 ) was compared between diabetic and n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2fd289b6-a4a2-53b7-884f-d5f565d24017
DOI: 10.1101/2023.01.23.525218

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemiaDOI 10.1101/2023.01.23.525218Read

High glucose treatment induced nuclei aggregation of microvascular endothelial cells via foxo1a-klf2a pathwaySemantic proximity Read

Aquaporin-1 Promotes Angiogenesis, Fibrosis, and Portal Hypertension Through Mechanisms Dependent on Osmotically Sensitive MicroRNAsSemantic proximity Read

Vasoregression: A Shared Vascular Pathology Underlying Macrovascular And Microvascular Pathologies?Semantic proximity Read

Differential microvascular endothelial cell responses in the retina in diabetes compared to the heart and kidneys, a spatial transcriptomic analysisSemantic proximity Read

Glut1/SLC2A1 is crucial for the development of the blood‐brain barrier in vivoSemantic proximity Read

Renal microvascular damaged in diabetes mellitus with hyperlipidemia through the regulation of MAMs by PACS2 in endothelial cellSemantic proximity Read

Analysis of long non-coding RNA expression profiles in high-glucose treated vascular endothelial cellsSemantic proximity Read

Integrated transcriptome and proteome analyses unveil cytoskeletal alterations in an endothelial model of monogenic diabetes.Semantic proximity Read

Vascular defects of <i>DYRK1A</i> knockouts are ameliorated by modulating calcium signaling in zebrafishSemantic proximity Read

Advancing Diabetic Retinopathy Research: Analysis of the Neurovascular Unit in ZebrafishSemantic proximity Read

Human iPSC-derived brain endothelial microvessels in a multi-well format enable permeability screens of anti-inflammatory drugsSemantic proximity Read

A global profile of glucose-sensitive endothelial-expressed long non-coding RNAsSemantic proximity Read