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East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer disease

2022-10-26

Abstract excerpt

Peptic ulcer disease (PUD) refers to acid-induced injury of the digestive tract, occurring mainly in the stomach (gastric ulcer; GU) or duodenum (duodenal ulcer; DU). We conducted a large-scale cross-ancestry meta-analysis of PUD combining genome-wide association studies with four Japanese and two European studies (52,032 cases and 905,344 controls), and discovered 25 novel loci highly concordant across ancestries...

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Literature Corpus work
2fb617c8-796c-57da-9624-790ed01a1ea5
DOI
10.1101/2022.10.25.22281344
Open publication

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East Asian-specific and cross-ancestry genome-wide meta-analyses provide mechanistic insights into peptic ulcer diseaseDOI 10.1101/2022.10.25.22281344
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