Article

Production of β-PheRS fragments correlates with food avoidance and slow growth, and is suppressed by the appetite-inducing hormone CCHa2

2023-01-12

Abstract excerpt

The housekeeping tRNA synthetases play many non-canonical roles with diverse functions. The phenylalanyl-tRNA synthetase (PheRS/FARS) is an α 2 β 2 tetramere. Recently, human patients with mutations in FARSB , the homolog of β-PheRS in Drosophila, have been reported to display problems gaining weight. Here, we show in Drosophila that overexpressing the β subunit in the context of the complete PheRS leads to la...

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Literature Corpus work: 2f8e66a9-97b2-5d07-82c0-b99ba3a8f4f1
DOI: 10.1101/2023.01.11.523627

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Production of β-PheRS fragments correlates with food avoidance and slow growth, and is suppressed by the appetite-inducing hormone CCHa2DOI 10.1101/2023.01.11.523627Read

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