Article
Two putative glutamate decarboxylases of Streptococcus pneumoniae as possible antigens for the production of anti-GAD65 antibodies leading to type 1 diabetes mellitus
2023-01-16
Abstract excerpt
Type 1diabetes mellitus (T1DM) has been increasing in prevalence in the last decades and has become a global burden. Autoantibodies against human glutamate decarboxylase (GAD65) are among the first to be detected at the onset of T1DM. Diverse viruses have been proposed to be involved in the triggering of T1DM because of molecular mimicry, i.e. , similarity between some viral proteins and one or more epitopes of GA...
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Identifiers and source
- Literature Corpus work
- 2f820163-c2b3-5fb3-8826-e1bd8f78dd92
- DOI
- 10.21203/rs.3.rs-2468797/v1
