Article

Broadly-reactive IgG responses to heterologous H5 prime-boost influenza vaccination are shaped by antigenic relatedness to priming strains

2021-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Prime-boost vaccinations of humans with different H5 strains have generated broadly protective antibody levels. However, the effect of an individual’s H5 exposure history on antibody responses to subsequent H5 vaccination is poorly understood. To investigate this, we analyzed the IgG response to H5 A/Indonesia/5/2005 (Ind05) vaccination in three cohorts: (1) a double primed group that received t...

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Literature Corpus work: 2f2d4278-847a-5c9b-8ebe-2790164e3d98
DOI: 10.1101/2021.04.09.439262

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