Article

Characterising antibody kinetics from multiple influenza infection and vaccination events in ferrets

2018-09-07

Abstract excerpt

The strength and breadth of an individual’s antibody repertoire are important predictors of their response to influenza infection or vaccination. Although progress has been made in understanding qualitatively how repeated exposures shape the antibody mediated immune response, quantitative understanding remains limited. We developed a set of mathematical models describing short-term antibody kinetics following infl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ad98e93a-8a29-5c84-947e-6317daf05783
DOI: 10.1101/411751

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterising antibody kinetics from multiple influenza infection and vaccination events in ferretsDOI 10.1101/411751Read

Timescales of influenza A/H3N2 antibody dynamicsSemantic proximity Read

Influenza virus infection history drives and shapes antibody responses to influenza vaccinationSemantic proximity Read

A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virusSemantic proximity Read

Explicit Modelling of Antibody Levels for Infectious Disease Simulations in the Context of SARS-CoV-2Semantic proximity Read

Long-term intrinsic cycling in human life-course antibody responses to influenza A(H3N2)Semantic proximity Read

Immune Imprinting in the Influenza Ferret ModelSemantic proximity Read

Influenza virus immune imprinting dictates the clinical outcomes in ferrets challenged with highly pathogenic avian influenza virus H5N1Semantic proximity Read

Cross-reactive anti-hemagglutinin (HA) IgG responses are shaped by previous long-interval monovalent H5 vaccination and highly correlated with HA antigenic distanceSemantic proximity Read

Asynchrony between virus diversity and antibody selection limits influenza virus evolution.Semantic proximity Read

Broadly-reactive IgG responses to heterologous H5 prime-boost influenza vaccination are shaped by antigenic relatedness to priming strainsSemantic proximity Read

A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virusSemantic proximity Read

A novel modelling framework for immunity-driven epidemics of non-sterilising infectionsSemantic proximity Read