Article

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer

2023-03-23

Abstract excerpt

Prostate cancer (PCa) is the second leading cause of cancer death for men in the United States. While organ-confined disease has reasonable expectation of cure, metastatic PCa is universally fatal upon recurrence during hormone therapy, a stage termed castration-resistant prostate cancer (CRPC). Until such time as molecularly defined subtypes can be identified and targeted using precision medicine, it is necessary...

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Literature Corpus work: 2f2bcea6-9a93-5e16-a546-fd3760ed1327
DOI: 10.1101/2023.03.23.533944

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